Most Important Clinical Facts About Zoloft Side Effects

Zoloft is one of the most prescribed drugs for depression management in the US. Zoloft efficacy has led to irrational use of the drug. Some of the clinicians prescribe the drug in most drug treatment programs that can be managed by other drugs. Apart from depression, Zoloft is effective in treating sexual dysfunction in men and premenstrual dysphoric condition in women. There is a need for both the prescribing clinicians and patients taking this antidepressant to be aware of the possible side effects that come along with use of this drug.


Zoloft Side Effects

Zoloft side effects may vary in different situations. The side effects experienced by male patients are not always the same the side effects experienced by their female counterparts. Also, the side effects experienced by adult patients differ from the ones experienced by adults. The most common general side effects that may be experienced by all the patients taking Zoloft are:

  1. Inflammation of the sinus.
  2. Mood swings
  3. Weight loss or gain
  4. Paradoxical behavior
  5. Fever
  6. Dehydration leading to dry mouth
  7. Lack of sleep
  8. Loss of appetite
  9. Throbbing headache
  10. Nausea


Specific Zoloft side effects experienced by women

In some instances, Zoloft affects normal hormonal activity leading to hormonal imbalance and also affects female genitourinary system. This results to altered menstrual cycle leading to delayed menstruation. Some of the side effects stop immediately when the drug is withdrawn. However, some of the effects take time to diminish such as the menstrual cycle might take time to become regular.


Other side effects experienced by female are:

  • Abdominal spasms
  • Discharge of milk from the breasts
  • Breast tenderness
  • Sleep disturbance
  • Difficulty in achieving orgasm


Zoloft side effects in men

Like their female counterparts, men may also experience hormonal disturbances resulting from use of Zoloft. This leads to sexual dysfunction such as reduced sexual libido or erectile dysfunction.


Other experiences in men include

  • constipation
  • pain in lower abdomen
  • muscle cramps.


Zoloft side effects in children

Children do experiences the similar side effects as in adults. However, there are certain side effects experienced only by children. These side effects are:
1). Hyperactivity
2). Purpura: This is bloody bruises spotted on the child’s skin or nose
3). Frequent urination due to inability to control urine bladder
4). Inflammation and infection of the sinus.


Management of the Zoloft side effects

To avoid adverse reactions the side effects must be managed efficiently. In most cases the best management is discontinuing the medication and providing an alternate medication. For a patient it is vital to contact your family physician immediately you experience any of the side effects. The management depends on the severity of the side effects. Hormonal irregularities can be rectified by hormonal medicines or left for the body to readjust back to its normal hormonal activity. Dehydration is easily managed by taking a lot of water.


The side effects must be managed effectively to avoid adverse reactions that would endanger the patient’s life. It is also significant for the clinicians to evaluate carefully patients past reaction to Zoloft and skive away from the possible side effects. Hence, a safe alternative medication can be prescribed to manage the patient’s condition.